Reviewed by Peptide Treatments Medical Advisory Board (Medical Advisory Board)

PT-141: Regulatory Status

Current legal and regulatory status for PT-141 across jurisdictions. This page reflects the most recent verified information and is updated as regulatory actions occur.

Back to PT-141 overview

United States

FDA Approved

Prescription required

Recent Regulatory Action

AMAG Pharmaceuticals acquired by Covis Pharma (2020); Vyleesi distribution continues.

FDA-approved as Vyleesi (bremelanotide, 2019) for treatment of hypoactive sexual desire disorder (HSDD) in premenopausal women. Self-administered subcutaneous injection. Not for daily use — maximum 8 doses per month.

FDA Pathway: NDA 210557 (Vyleesi)
Last verified:

What This Means

Reclassification is not the same as FDA approval.

Even if PT-141 moves to Category 1, it remains an off-label therapeutic that requires physician supervision. Category 1 means it can be compounded under section 503A — it does not confer approved-drug status.

PT-141 Overview

Uses, benefits, evidence, and monitoring.

Contraindications

Safety profile and drug interactions.

Evidence Summary

Clinical trial data and evidence tiers.