Reviewed by Peptide Treatments Medical Advisory Board (Medical Advisory Board)

LL-37: Contraindications & Drug Interactions

Safety information for LL-37 including known contraindications, drug interactions, and important precautions.

Back to LL-37 overview

Contraindications

  • Autoimmune conditions (theoretical exacerbation of inflammatory response)
  • Pregnancy and breastfeeding

Drug Interactions (3 interactions)

Important: This table summarizes known and theoretical interactions. Always consult a healthcare provider before combining LL-37 with any medication.
Drug Classification Mechanism
Immunosuppressants Theoretical LL-37 activates innate immune pathways — may counteract immunosuppressive therapy
Topical antibiotics Theoretical Potential synergistic antimicrobial effect when combined
Other antimicrobial peptides Theoretical Additive or synergistic antimicrobial effects possible

Use our interactive Drug Interaction Checker for real-time lookup.