Reviewed by Peptide Treatments Medical Advisory Board
Tesamorelin: Side Effects & Safety
Known side effects, safety considerations, and adverse reaction data for Tesamorelin.
Back to Tesamorelin overviewData source: Side effects are based on FDA-approved labeling for related indications.
Reported Side Effects (7 items)
| # | Side Effect |
|---|---|
| 1 | Injection site reactions (14-16%) |
| 2 | Arthralgia (9%) |
| 3 | Edema/peripheral swelling (3%) |
| 4 | Myalgia (2%) |
| 5 | Headache (2%) |
| 6 | Elevated IGF-1 (4-6%) |
| 7 | Nausea (2%) |
Known Drug Interactions
Important: Only documented and contraindicated interactions are shown here. View all interactions including theoretical →
| Drug | Classification | Mechanism |
|---|---|---|
| Glucocorticoids | Documented | Corticosteroids may attenuate GH-releasing effects of tesamorelin |
| Growth hormone products | Documented | Additive GH/IGF-1 effects — avoid combination |
| IGF-1 therapy | Documented | Additive effects — avoid combination |