Reviewed by Peptide Treatments Medical Advisory Board
PCSK9 Inhibitors: Side Effects & Safety
Known side effects, safety considerations, and adverse reaction data for PCSK9 Inhibitors.
Back to PCSK9 Inhibitors overviewData source: These side effects are documented in FDA-approved prescribing information.
Reported Side Effects (7 items)
| # | Side Effect |
|---|---|
| 1 | Injection site reactions (2-6%, most common, generally mild) |
| 2 | Influenza-like symptoms (3-5%) |
| 3 | Upper respiratory tract infection (common) |
| 4 | Back pain (2-4%) |
| 5 | Diarrhea (2-4%) |
| 6 | Slight numerical increase in new-onset diabetes (not statistically significant in most trials) |
| 7 | Rare hypersensitivity reactions |
Known Drug Interactions
Important: Only documented and contraindicated interactions are shown here. View all interactions including theoretical →
| Drug | Classification | Mechanism |
|---|---|---|
| bile acid sequestrants | Documented | Separate administration by at least 1 hour to avoid absorption interference |