Reviewed by Peptide Treatments Medical Advisory Board (Medical Advisory Board)

Orforglipron: Bloodwork Guide

Recommended lab tests and biomarkers to monitor before, during, and after Orforglipron therapy. Testing schedules are based on clinical protocols and published monitoring guidelines.

Back to Orforglipron overview

Before Starting (2 tests)

Biomarker Expected Effect Retest
ALT/AST → normalizes Every 12 weeks
Lipid Panel → normalizes Every 24 weeks

During Treatment (3 tests)

Biomarker Expected Effect Retest
HbA1c ↓ decreases Every 12 weeks
Fasting Glucose ↓ decreases Every 4 weeks
Body Weight ↓ decreases Every 4 weeks