MK-677: Regulatory Status
Current legal and regulatory status for MK-677 across jurisdictions. This page reflects the most recent verified information and is updated as regulatory actions occur.
Back to MK-677 overviewUnited States
Research Only
Compounding status: available through research chemical suppliers. WADA: prohibited (S2 — peptide hormones, growth factors, and related substances). not approved in any jurisdiction. Widely available as a "research chemical." China banned MK-677 in 2020 as part of SARMs/peptide enforcement. FDA has issued warning letters to companies selling MK-677 as a dietary supplement.
What This Means
Reclassification is not the same as FDA approval.
Even if MK-677 moves to Category 1, it remains an off-label therapeutic that requires physician supervision. Category 1 means it can be compounded under section 503A — it does not confer approved-drug status.