Reviewed by Peptide Treatments Medical Advisory Board (Medical Advisory Board)
Mazdutide: Side Effects & Safety
Known side effects, safety considerations, and adverse reaction data for Mazdutide.
Back to Mazdutide overviewData source: Side effects are based on FDA-approved labeling for related indications.
Reported Side Effects (8 items)
| # | Side Effect |
|---|---|
| 1 | Nausea (common, consistent with GLP-1 class) |
| 2 | Vomiting (common) |
| 3 | Diarrhea (common) |
| 4 | Decreased appetite (common) |
| 5 | Constipation (common) |
| 6 | Theoretical risk of gastroparesis (GLP-1 class effect) |
| 7 | Theoretical risk of thyroid C-cell tumors (GLP-1 class effect) |
| 8 | All Phase 2/3 data from Chinese populations — safety in other ethnic groups not established |
Known Drug Interactions
Important: Only documented and contraindicated interactions are shown here. View all interactions including theoretical →
| Drug | Classification | Mechanism |
|---|---|---|
| insulin and sulfonylureas | Documented | Additive hypoglycemic effect from GLP-1-mediated insulin secretion — dose reduction of concomitant insulin/sulfonylurea may be required |