Reviewed by Peptide Treatments Medical Advisory Board (Medical Advisory Board)
GnIH: Evidence Summary
Evidence summary for GnIH across studied indications. Each indication is graded using our evidence tier system based on the quality and quantity of available clinical data.
Back to GnIH overview| Indication | Evidence Tier | Trial Count | Summary |
|---|---|---|---|
| Reproductive hormone regulation | Tier D | 0 | Animal data only — zero human studies |
| Contraception (theoretical) | Tier D | 0 | Logical extension of mechanism — never studied |
References (3)
- Discovery and characterization of GnIH — Ubuka T, et al. . Frontiers in Endocrinology (2014) PMID: 25177268
- RFRP-3 expression in human hypothalamus — Kiyohiko T, et al. . Endocrinology (2009) PMID: 20027225
- Sleep regulation and GnIH-related peptides in mice — Spier AD, de Lecea L . Molecular and Cellular Endocrinology (2006)