Reviewed by Peptide Treatments Medical Advisory Board
GHRP-6: Side Effects & Safety
Known side effects, safety considerations, and adverse reaction data for GHRP-6.
Back to GHRP-6 overviewData source: Side effect data comes from clinical trials, preclinical research, and anecdotal reports. No FDA-approved labeling exists for this compound.
Reported Side Effects (6 items)
| # | Side Effect |
|---|---|
| 1 | Pronounced appetite increase — most notable effect |
| 2 | Injection site reactions (redness, discomfort) |
| 3 | Headache — mild to moderate |
| 4 | Transient cortisol elevation |
| 5 | Transient prolactin elevation |
| 6 | Water retention — more frequent than other GHRPs |
Known Drug Interactions
Important: Only documented and contraindicated interactions are shown here. View all interactions including theoretical →
| Drug | Classification | Mechanism |
|---|---|---|
| Somatostatin analogs | Contraindicated | Directly antagonizes GH-releasing action |
| Glucocorticoids | Documented | Corticosteroids blunt GH response to GHRP-6 |