Reviewed by Peptide Treatments Medical Advisory Board (Medical Advisory Board)
GHRP-2: Evidence Summary
Evidence summary for GHRP-2 across studied indications. Each indication is graded using our evidence tier system based on the quality and quantity of available clinical data.
Back to GHRP-2 overview| Indication | Evidence Tier | Trial Count | Summary |
|---|---|---|---|
| Growth hormone secretion | Tier B | 8 | Potent GH secretagogue with well-characterized dose-response in clinical studies |
| Appetite stimulation | Tier C | 2 | Stimulates ghrelin receptor, increasing appetite — potential in cachexia |
References (7)
- Pharmacotherapy in Cachexia: A Review of Endocrine Abnormalities and Steroid Pharmacotherapy. . Journal of pain & palliative care pharmacotherapy (2022) PMID: 35758863
- The effect of growth hormone releasing peptide-2 on upper gastrointestinal contractile activity and food intake in conscious dogs. . Journal of gastroenterology (2009) PMID: 19271111
- Anti-inflammatory effect of the ghrelin agonist growth hormone-releasing peptide-2 (GHRP-2) in arthritic rats. . American journal of physiology. Endocrinology and metabolism (2005) PMID: 15507538
- Pralmorelin testing for growth hormone deficiency. — Kojima M, et al. . Endocrine Journal (2004) PMID: 15230633
- Growth hormone-releasing peptide-2 reduces inward rectifying K+ currents via a PKA-cAMP-mediated signalling pathway in ovine somatotropes. . The Journal of physiology (2002) PMID: 12456822
- GH-releasing effect of GHRP-2. — Hashimoto K, et al. . Clinical Endocrinology (2002) PMID: 12030918
- Growth hormone responses during strenuous exercise: the role of GH-releasing hormone and GH-releasing peptide-2. . Medicine and science in sports and exercise (2000) PMID: 10912886