Reviewed by Peptide Treatments Medical Advisory Board (Medical Advisory Board)

GHK Peptide: Evidence Summary

Evidence summary for GHK Peptide across studied indications. Each indication is graded using our evidence tier system based on the quality and quantity of available clinical data.

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Indication Evidence Tier Trial Count Summary
Gene expression modulation Tier D 0 In vitro data only — most studies used GHK-Cu, not GHK alone
Skin aging/wound healing Tier D 0 No copper-free GHK human trials — all data from GHK-Cu studies
Anti-inflammatory effects Tier D 0 Cell culture data only — not tested in humans

References (3)

  1. GHK-Cu and gene expression modulation in skin — Pickart L, Vasquez-Soltero JM, Margolina A . Cosmetics (2017)
  2. GHK peptide as a natural modulator of multiple cellular pathways — Pickart L, Vasquez-Soltero JM, Margolina A . International Journal of Molecular Sciences (2018)
  3. Role of copper peptide GHK-Cu in skin regeneration — Hussain M, et al. . Journal of Drugs in Dermatology (2015)