Reviewed by Peptide Treatments Medical Advisory Board (Medical Advisory Board)

GHK-Cu: Evidence Summary

Evidence summary for GHK-Cu across studied indications. Each indication is graded using our evidence tier system based on the quality and quantity of available clinical data.

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Indication Evidence Tier Trial Count Summary
Wound healing Tier C 3 Topical application accelerates wound closure in small trials
Skin aging / rejuvenation Tier C 4 Increases collagen synthesis and skin thickness in controlled studies
Hair loss Tier D 1 Preclinical evidence suggests follicle stimulation; human data limited

References (5)

  1. Immunostimulatory Hydrogel with Synergistic Blockage of Glutamine Metabolism and Chemodynamic Therapy for Postoperative Management of Glioblastoma. . Advanced science (Weinheim, Baden-Wurttemberg, Germany) (2025) PMID: 39976234
  2. An Assessment of the Safety, Efficacy, and Tolerability of a Novel Scalp Treatment Regimen Combining a Hydroxy Acid-Based Scrub and Copper Tripeptide Serum in the Management of Seborrheic Dermatitis in Adults. . Cureus (2024) PMID: 39449909
  3. Microneedle-Mediated Delivery of Copper Peptide Through Skin. . Pharmaceutical research (2015) PMID: 25690343
  4. Using Aldara, copper peptide, and niacinamide for skin care. . Aesthetic surgery journal (2004) PMID: 19336143
  5. DNA- and protein-scission activities of ascorbate in the presence of copper ion and a copper-peptide complex. . Journal of biochemistry (1983) PMID: 6654857