Reviewed by Peptide Treatments Medical Advisory Board (Medical Advisory Board)

Crystallin: Evidence Summary

Evidence summary for Crystallin across studied indications. Each indication is graded using our evidence tier system based on the quality and quantity of available clinical data.

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Indication Evidence Tier Trial Count Summary
Cataract biomarker Tier C 0 Validated as diagnostic biomarker, not a therapeutic
Retinal protection Tier D 0 Animal gene therapy studies only — no human trials
Anti-aging therapeutic Tier D 0 No therapeutic development — biomarker research only

References (3)

  1. Crystallin in lens biology and pathology — Andley UP . Progress in Retinal and Eye Research (2007)
  2. Crystallin changes in human cataractous lenses — Pasupuleti N, et al. . Molecular Vision (2013) PMID: 8405188
  3. Alpha-crystallin overexpression protects retina in mouse model — Yaung J, et al. . Experimental Eye Research (2007)