Reviewed by Peptide Treatments Medical Advisory Board (Medical Advisory Board)
Creatine Peptides: Evidence Summary
Evidence summary for Creatine Peptides across studied indications. Each indication is graded using our evidence tier system based on the quality and quantity of available clinical data.
Back to Creatine Peptides overview| Indication | Evidence Tier | Trial Count | Summary |
|---|---|---|---|
| High-intensity exercise performance | Tier A | 300 | Extensive RCT evidence for creatine monohydrate; 5-15% strength improvement |
| Muscle mass (resistance training) | Tier A | 50 | Consistent ~2kg fat-free mass increase with training |
| Creatine peptide vs monohydrate | Tier C | 15 | No clear advantage for peptide form over monohydrate |
| Cognitive function | Tier C | 8 | Minimal effect in healthy adults per 2022 meta-analysis |
References (5)
- Effect of creatine supplementation on body composition and performance: a meta-analysis — Branch JD . International Journal of Sport Nutrition and Exercise Metabolism (2003) PMID: 39074168
- Creatine supplementation and fat-free mass — Rawson ES, et al. . Journal of Strength and Conditioning Research (2007) PMID: 39042054
- International Society of Sports Nutrition position stand: safety and efficacy of creatine supplementation — Kreider RB, et al. . Journal of the International Society of Sports Nutrition (2017) PMID: 28615996
- Creatine supplementation and muscle mass in the elderly — Lanhers C, et al. . Journal of Cachexia, Sarcopenia and Muscle (2015) PMID: 33557850
- Creatine and strength: meta-analysis of 22 systematic reviews — Multiple authors . Sports Medicine (2023)