PeptideTreatments
Reviewed by Peptide Treatments Medical Advisory Board (Medical Advisory Board)

AOD-9604: Evidence Summary

Evidence summary for AOD-9604 across studied indications. Each indication is graded using our evidence tier system based on the quality and quantity of available clinical data.

Back to AOD-9604 overview
Indication Evidence Tier Trial Count Summary
Weight loss / fat reduction Tier C 6 6 completed human trials (900+ participants) showed modest fat reduction but pivotal Phase IIb failed primary endpoint
Osteoarthritis Tier C 2 Early-phase trials suggest cartilage repair potential

References (10)

  1. Effect of Intra-articular Injection of AOD9604 with or without Hyaluronic Acid in Rabbit Osteoarthritis Model. . Annals of clinical and laboratory science (2015) PMID: 26275694
  2. Analytical approaches for the detection of emerging therapeutics and non-approved drugs in human doping controls. . Journal of pharmaceutical and biomedical analysis (2014) PMID: 24906629
  3. Current updates in the medical management of obesity. . Recent patents on endocrine, metabolic & immune drug discovery (2012) PMID: 22435392
  4. [Obesity: a review of currently used antiobesity drugs and new compounds in clinical development]. . Postepy higieny i medycyny doswiadczalnej (Online) (2007) PMID: 17971763
  5. Potential role of new therapies in modifying cardiovascular risk in overweight patients with metabolic risk factors. . Obesity (Silver Spring, Md.) (2006) PMID: 16931496
  6. Obesity drugs in clinical development. . Current opinion in investigational drugs (London, England : 2000) (2006) PMID: 16625817
  7. Gateways to clinical trials. . Methods and findings in experimental and clinical pharmacology (2005) PMID: 15834452
  8. Gateways to clinical trials. . Methods and findings in experimental and clinical pharmacology (2003) PMID: 14685303
  9. Gateways to clinical trials. . Methods and findings in experimental and clinical pharmacology (2003) PMID: 14571286
  10. The effects of human GH and its lipolytic fragment (AOD9604) on lipid metabolism following chronic treatment in obese mice and beta(3)-AR knock-out mice. . Endocrinology (2001) PMID: 11713213